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Reactive arthritis (ReA) is the second most common form of arthritis and shows chronic progression in up to 40 % of cases. An early diagnosis based on a careful clinical case history and laboratory work-up is therefore essential. Especially Salmonella infections caused by pathogens with identical O-antigens (group B and D) are closely linked to ReA. High IgA-class antibody titres against these Salmonella serotypes are a highly sensitive marker for the diagnosis of ReA. As the widely used Widal agglutination test mainly detects IgM-class antibodies and therefore has a low sensitivity, it is therefore not suitable for this purpose. On this basis, IMTEC has developed a unique test system for the reliable diagnosis of reactive arthritis.
The IMTEC Anti-Salmonella ELISA utilizes lipopolysaccharides specific for S. typhimurium and S. enteritidis and thereby ensures a sensitivity superior to other test systems.
Advantages of the Anti-Salmonella ELISA: