By subscribing to our mailing list you will always be updated about the latest products.
Monday to Friday
9:00AM - 5:00PM
10:00AM - 3:00PM
JUser: :_load: Unable to load user with ID: 976
Vasculitis is a general term for a group of diseases that involve inflammation in blood vessels. Blood vessels of all sizes may be affected, from the largest vessel in the body (the aorta) to the smallest blood vessels in the skin (capillaries). The size of the blood vessel affected varies according to the specific type of vasculitis.
When a blood vessel is inflamed, it can narrow or close off. This limits or prevents blood from getting through the vessel. Rarely, the blood vessel will stretch and weaken, causing it to bulge. This bulge is known as an aneurysm. The disruption in blood flow from inflammation can damage the body's organs. Signs and symptoms depend on which organs have been damaged and the extent of the damage.
Typical symptoms of inflammation, such as fever and general aches and pains, are common among people who have vasculitis. Wegener's Granulomatosis (WG) is closely associated with antineutrophil cytoplasmic autoantibodies (ANCA), particularly those directed to proteinase 3 (PR3). ANCAs directed to myeloperoxidase (MPO) are associated with microscopic polyangiitis (MPA) and Churg-Strauss syndrome. PR3-ANCA associated vasculitis differs from MPO-ANCA associated vasculitis particularly in the occurrence of granulomatous inflammation and more widespread disease in the former condition.